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Broccoli protect from a lung cancer

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Broccoli helps the immune system to remove from lung disease-causing bacteria, experimentally established staff at Johns Hopkins University in Baltimore (Maryland, USA).

To ensure proper operation of the lungs, white blood cells - macrophages - remove foreign matter and bacteria that can accumulate there and cause infection. This "purification system" is faulty in smokers and people with chronic obstructive pulmonary disease (COPD, a combination of emphysema and bronchitis), which suffer from frequent infections.

Researchers have established that the chemical path in the lungs called NRF2, involved in the activation of macrophages, is destroyed by smoking. It was also found that sulforaphane - plant chemicals produced by broccoli, cauliflower and other cruciferous vegetables is damaged - is able to restore the path NRF2.

At the first stage of the experiment, scientists have defective macrophages from the lungs 43 people with COPD and treated them with two strains of bacteria commonly causing infections associated with COPD. In the presence of sulforaphane way NRF2 became stronger, and the ability of macrophages to recognize and absorb the bacteria recovered.

In the second phase, researchers exposed mice to environmental tobacco smoke for a week or six months. The result showed that both groups increased bacterial colonization of the lung, similar to that observed during COPD. But after treatment, mice sulforafanom their lungs became more clear in the bacterial respect. According to experts, not only sulforaphane activated a greater number of macrophages, but also improves the functionality already present cells.

Sulforaphane "lives " in the broccoli in the form of a substance precursor is converted into an active part under the influence of enzymes present in saliva, and intestinal bacteria. The concentration of this enzyme in all people are different, and the dose of sulforaphane, derived from food, each also has its own. To definitively determine whether a beneficial effect of sulforaphane-containing products on the immune defense is required to conduct experiments on humans.

Baltimore team of specialists has already begun the second phase of clinical trials of sulforaphane in patients with COPD. The purpose of this study - to determine whether this substance improves lung function and the results will be obtained no earlier than three years.

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Big beer drinkers at big risk for stomach cancer

Heavy beer drinkers have an increased risk of gastric cancer, especially if they possess a certain gene variant, a new study suggests.

People who drink two to three beers a day for many years have a 75 percent increased risk of gastric cancer, and those who have the gene variant called rs1230025 but aren't heavy drinkers have a 30 percent higher risk of gastric cancer, compared with people who drank less than a beer daily, the study showed.

But people who are both chronic heavy beer drinkers and possess rs1230025 have a more than 700 percent increased risk of gastric cancer compared with people who consume less than one drink a day and don't have the gene variation, said study researcher Eric Duell, a senior epidemiologist at the Catalan Institute of Oncology in Barcelona, Spain. The gene variant is common and is present in about 20 percent of the general population, he said.

However, wine and liquor don't seem to carry the same gastric cancer risks, Duell said.

"The share of the risk from total alcoholic beverages seems to be dominated by the alcohol contributed from beer consumption," Duell told MyHealthNewsDaily. "Consumption of wine and liquor did not show elevated risk of gastric cancer," which could be because heavy drinkers may be more likely to drink beer than other alcoholic beverages.

The findings are correlated, meaning there is a link between beer drinking and gastric cancer risk, but the results can't speak to whether one caused the other or some other factor is responsible.

Duell and his colleagues analyzed the alcohol consumption and gastric cancer status of 521,000 people ages 35 to 70, who were part of the European Prospective Investigation into Cancer and Nutrition in 1992 and 1998. Researchers noted whether the study participants consumed wine, beer or liquor regularly, and the location and severity of their gastric cancer, if any.

Researchers found that people who regularly consumed more than 60 grams of alcohol (equivalent to four to five beers) a day had a 65 percent higher risk of developing gastric cancer over the study period than people who regularly drank 0.1 to 4.9 grams of alcohol a day (less than a beer ).

When researchers looked purely at beer consumption (instead of general alcohol consumption), gastric cancer risk increased, as it did when the researchers looked at people who were heavy drinkers and had the gene variant rs1230025.

Gastric cancer, also known as stomach cancer, caused 10,570 deaths in the United States last year and usually strikes people ages 65 and older, according to the National Cancer Institute. One in 114 people will be diagnosed with the cancer in their lifetime.

Researchers aren't sure why only beer seems to produce this gastric cancer risk and not wine or liquor, Duell said, but it could be a combination of higher consumption of beer than wine or liquor, and the specific carcinogens that are produced when beer is metabolized.

When alcohol is metabolized in the body, a known carcinogen called acetaldehyde is produced. Beer in particular also contains low levels of a known animal carcinogen called N-nitrosodimethylamine (NDMA). Prolonged exposure to both acetaldehyde and NDMA, via daily beer drinking, could play a role in gastric cancer risk, Duell said.

And if heavy drinkers tend to drink more beer than wine or liquor, then those low amounts of acetaldehyde and NDMA could build up to increase gastric cancer risk, he said.
Because of these risks, people should avoid heavy consumption of alcohol, Duell said, though light to moderate consumption of alcohol is OK.
Next, Duell and his colleagues hope to do additional research to find more gene variants that could have an effect on gastric cancer risk.

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Berry, raspberry and simple seeds are killing the cancer

Properties of berries, raspberries studied American scientists from Clemson University. The result was obtained by a unique result: it turned out that Berry is endowed with a number of useful properties. One of them - anti cancerous.

Experts have created a raspberry extract, after which he worked on the tumor cells in the rat intestine. It was finally destroyed at least 90% of malignant cells. The fact that the berry in its composition contains antioxidants, has been known previously. But doctors say with confidence that it is not they are working on cancer, and the unknown substance. To find out exactly what will be carried out further investigations.

On the anti-cancer properties of black raspberry has been known for a long time. Now experts clarify helpful if all varieties of raspberries, and whether the forces of all the cells to neutralize the deadly disease.

But that's not all. Those American scientists, but the University of Illinois, conducted the study, the results showed: number of tumors - colon, ovarian, breast, skin and lungs - are able to inhibit simple seeds.

Study were smokers. Throughout the year birds were added to the diet simple seeds. As a result, the number of tumors in chickens, even late-stage disease, decreased significantly. In addition, it was markedly reduced dissemination of ovarian cancer. All the birds regained normal weight, reaching optimal performance.

Experts say that if these studies will be further confirmed, in the future, sunflower seeds may be able to use as an adjuvantfor the treatment for cancer.

As previously reported, in the prevention of formation of cancer cells showed a high efficiency retinoic acid - a derivative of vitamin A. This acid has shown correlation with beta-receptor acid RAR-H, which indicates an increase in the positive dynamics in the fight against cancer.

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How does RADIATION ON THE HUMAN BODY

Disaster in Japan has forced humanity to speak again with anxiety about the dangers of radiation. But the real horror is that to understand this without special knowledge is impossible.

Fear is all incomprehensible. To sort out what on television telling the experts, the ordinary man more difficult because the measuring radiation levels and to assess its risks are still using a dozen different units. X-rays, bery (the biological equivalent of radiation), curie, Grays, Becquerel, Sievert - they are so many precisely because for many decades, all work on nuclear issues, strictly confidential, and each country has its unit of measurement.

In recent years, to measure radiation levels to apply the new international unit - the sievert and thousands and millions of shares. In these units report to the data on the situation and the Japanese. The true meaning of this unit only understand physicists, but we need to know that the maximum safe dose for humans is 100 millisieverts per hour. Natural background radiation is from 12 to 16 micro sievert per hour.

Now, the real danger. Radiation dose of 1-2 Sievert per hour (ie 1-2 million micro sievert!) Can cause radiation sickness. Single irradiation dose of 3.5 sievert damages the bone marrow so much that without adequate care for a month or two are killed every other person. Higher doses of damaging the lungs and gastrointestinal tract - the death occurs within 10-20 days. A dose higher than 15 sievert can kill a person in a matter of days.

When hydrogen explosion at a Japanese nuclear power plant in the atmosphere were radioactive iodine and cesium. The half-life of iodine - 8 days, that is, a week later the dose is reduced exactly by half. And after 40 days it will be completely safe. The half-life of cesium is 30 years old, which means that, falling to the ground from the atmosphere, it will be a long time to accumulate in the environment - plants, animals and humans. In the body it penetrates the respiratory system and digestion, accumulates in muscle and liver. Biological half-life of cesium from the body considered equal to 70 days.

That is, if he ceases to act in person with air and food, we finally cleared the organism from him about a year. But in reality, this time may be more or less - a lot depends on health, nutrition, use of different sorbents that bind him and excreted. In this capacity, using barium sulfate, sodium alginate, and others. To calculate the radiation dose specifically to each individual, to the radiation background is multiplied by the time that people spent in contaminated areas.

For emergency prevention of radiation sickness usually applied iodine. He quickly accumulated in the thyroid gland, radioactive iodine, and there's just no room left. That is why the Japanese authorities have ordered to give tablets containing iodine, all the evacuees from the area of the accident.

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FDA OKs new 3-D breast scan, risks unclear

Better detection carries trade-off of more radiation exposure. U.S. health officials have approved Hologic Inc's 3-D mammogram system in hopes that it may help doctors better detect and diagnose breast cancer, even though women may be exposed to more radiation.

The device, an upgrade to the company's already approved 2-D system, offers physicians a more detailed look at the breast to see any possible anomalies, the Food and Drug Administration said on Friday.
Shares of Hologic were up 1.3 percent at $19.98 in afternoon Nasdaq trading after the news.

Traditional mammograms are still the best way to find breast cancer, the FDA said in a statement, but the limited technology requires some women to have additional testing. Reviewing an additional 3-D image helped doctors find more cancers than with 2-D images alone, it said.
However, the additional 3-D testing does double the amount of radiation given to patients and "there is uncertainty for radiation risk estimates," FDA said.

Still, the more-detailed scans "improved the accuracy with which radiologists detected cancers, decreasing the number of women recalled for a diagnostic work-up."

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